NHANES: National Health and Nutrition Examination Survey; SBP: systolic blood pressure; DBP: diastolic blood pressure; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; LDL: low-density lipoprotein; BMI: body-mass index; DM: diabetes; HF: heart failure; CHD: coronary heart disease; HBP: hypertension. The gene discussed is GPT; the disease is hypertensive disorder.