The most important finding of the study is that the glucocorticoids can significantly reduce acute pain and morphine consumption within 24 h, and decrease the postoperative level of CRP and IL-6 and the incidence of PONV, and achieve a better ROM and shorter LOS, without increasing continued high blood glucose and the risk of postoperative wound infection and venous thrombosis. This evidence concerns the gene IL6 and Venous thrombosis.