The precursors of goblet inflammatory cells are goblet 2 PLAU+ cells (Extended Data Fig. 2i) which expressed high levels of TMPRSS2 and ACE2 (Fig. 3c), suggesting that the virus targeted these cells and induced the generation of goblet inflammatory cells, which again expressed high levels of entry receptors and could thus be the target for further infection. The gene discussed is ACE2; the disease is infection.