Strong expression of C1GALT1, which encodes an enzyme required for the initial step of protein O-glycosylation [25], has been reported to predict poor prognosis of head and neck cancer, hepatocellular carcinoma, colon cancer, and ovarian cancer [24, 28, 29], possibly by regulating growth factor signaling. The gene discussed is C1GALT1; the disease is ovarian carcinoma.