PDGFRB and carcinoma: Since C1GALT1 is required for the stabilization of receptor-type phosphoproteins through glycosylation in other carcinomas [24, 28] and to maintain the total PDGFRβ protein expression level in osteosarcoma, we speculate that C1GALT1 may be required for the maintenance of PDGFRβ signaling through glycosylation in osteosarcoma.