In addition, a distinct chemokine levels in the circulation was also identified in PR3-ANCA AAV according to organ involvement21, and a prognostic role of CCL18 in ANCA-associated glomerulonephritis has been also described22, with the disease activity status predicting potential of CCR8, CXCL2, CXCL13, CCL5, CCL20, CCL22 suggested in AAV24,26–29. Here, PRTN3 is linked to glomerulonephritis.