To investigate whether BH3-mimetics can induce CICD in DLBCL, we screened different DLBCL cell lines sensitive to the BCL2 inhibitor ABT199, the BCL-XL inhibitor A1331852 or the MCL1 inhibitor S63845 [8] in the presence of the broad range caspase-inhibitor zVAD.fmk. This evidence concerns the gene BCL2 and diffuse large B-cell lymphoma.