PIN1 and neoplasm: The gene set enrichment analyses revealed a more significant positive enrichment of adaptive immune response, lymphocyte-mediated immunity and enhanced tumor antigen presentation upon combination treatment (Supplementary Fig. 10e, f), which was consistent with the immune response signatures in PIN1 KO cells (Supplementary Fig. 10g), suggesting that the combination treatment not only decreased PIN1 levels, but also increased tumor immunogenicity.