Immunoblot analysis of tumor extracts confirmed that cellular proteins that are highly expressed in GC B cells, including cyclin D3, GCSAM, TCL1, Myb, TCF3 and BACH2 are expressed at higher levels in the ΔEBNA2 + Myc lymphomas in comparison to the ΔEBNA2 alone lymphomas (Fig 5A–5C). Here, GCSAM is linked to lymphoma.