SRC and Burkitt lymphoma: To confirm that the combination of STAT3 and constitutively active Src is sufficient to induce LMP1 expression in human BL cells with type I latency, Mutu I BL cells were transfected with either a vector control plasmid, a STAT3 vector alone, a constitutively active Src vector alone, or the combination of STAT3 and constitutively active Src vectors (Fig 9B).