Similarly, Sinkre et al. described the case of a 38-year-old man with VHL disease, presenting with a carcinoid tumor of the gallbladder with lipid-containing clear cells, also initially interpreted as renal cell carcinoma, although it was positive for CgA, synaptophysin, cytoceratins, and inhibin [14]. This evidence concerns the gene SYP and hereditary clear cell renal cell carcinoma.