PTMA and nasopharyngeal carcinoma: To interrogate the involvement of the miR-370-5p/PTMA regulatory axis in circCOL1A1-mediated oncogenic pathways in NPC, we engineered SUNE1 and SNU46 cells with an overexpression construct for circCOL1A1 (oe-circCOL1A1) alongside siRNA targeting PTMA (si-PTMA).