Furthermore, we found that expression levels of ZAP70, FYN, GRAP2, ITK, and LCK as well as two further TCR pathway kinases, PLCG1 and LAT, were highest in human T-ALL cell lines compared with other hematopoietic cancer lines (Supplemental Figure 10B). Here, ITK is linked to hematopoietic and lymphoid cell neoplasm.