Based on the individual cancer stages of KIRP patients, DNASE1 expression was lower in stage 1 (p = 1.93e-07), stage 2 (p = 1.75e-07), stage 3 (p = 1.61e-07), stage 4 (p = 1.98e-07) in KIRP patients than in normal tissues. The gene discussed is DNASE1; the disease is cancer.