The patient had <i>KRAS</i> mutation and <i>MSS</i>-type colon cancer, and his PD-1<sup>+</sup>CD8<sup>+</sup> and CD3<sup>-</sup>CD19<sup>-</sup>CD14<sup>+</sup>CD16<sup>-</sup>HLA-DR were both positive. Here, CD19 is linked to malignant colon neoplasm.