Cysteinyl leukotriene receptor 1 (CYSLTR1) is a member of G-Protein-Coupled Receptor (GPCR) and is involved in the pathogenesis of several chronic inflammatory and immune disorders, including asthma 12, allergic rhinitis 13, rheumatoid arthritis (RA) 14, osteoarthritis 15, and multiple sclerosis (MS) 16. The gene discussed is CYSLTR1; the disease is osteoarthritis.