T cells play an irreplaceable role in the tumor immune microenvironment, which concerns whether immunotherapy can benefit patients, so we analyzed the correlation between LINC00313 expression and markers of different T cell subtypes (Th1-like cell: CXCL13, HAVCR2, IFNG, CXCR3, BHLHE40, and CD4; Naive T cell: CCR7, LEF1, TCF7, and SELL; Central memory T cell: CCR7, SELL, and IL7R; Resting Treg T cell: FOXP3, IL2RA; Effector T cell: CX3CR1, FGFBP2, and FCGR3A; Effector memory T cell: PDCD1, DUSP4, GZMK, GZMA, and IFNG; Effector Treg T cell: FOXP3, CTLA4, CCR8, and TNFRSF9). The gene discussed is CTLA4; the disease is neoplasm.