Furthermore, the difference in macrophage numbers in Eμ-Myc; Rock1 NC bone marrows was not replicated in an acute peritonitis model in which zymosan, a polysaccharide cell wall component derived from Saccharomyces cerevisiae (Cash et al., 2009), was injected into the peritoneal cavities of Eμ-Myc; Rock1 WT or Eμ-Myc; Rock1 NC mice to induce acute inflammation. The gene discussed is ROCK1; the disease is peritonitis.