The expression of the glycolytic proteins HK2, PKM2 and LDHA and the lactic acid concentration were obviously increased in the epithelial cells of PHT mice (Figure 7A), while HK2 and LDHA expression and the lactic acid concentration were decreased by Mdivi‐1 (Figure 7A). The gene discussed is LDHA; the disease is pulmonary hypertension, primary, 1.