MCC950 also repressed GC cell proliferation (Ki67 index: 34.60% in SGC7901 xenograft mouse models without MCC950 vs. 11.57% in those with MCC950) and NLRP3 activation (NLRP3 area: 17.47% in SGC7901 xenograft mouse models without MCC950 vs. 10.87% in those with MCC950) in SGC7901 mouse tumour models (Figure S6D,E). Here, MKI67 is linked to neoplasm.