Interestingly, feeding the mice a ketogenic diet with 90% saturated fat did not cause fatty liver or obesity in any of the LBPKI/KI, WT, or LBP−/− groups (Fig. 7v), which was consistent with our previous finding that LBP binds with PUFA-TG. Here, LBP is linked to obesity due to melanocortin 4 receptor deficiency.