A variant in the RAB32 gene, c.213C>G (Ser71Arg; NCBI Reference Sequence: NM_006834.5; dbSNP: rs200251693) was identified in three probands, which cosegregated with parkinsonism in their pedigrees (figure 2A).22, 23 In the first pedigree from Tunisia (TUN1), a sib-pair (III-3 and III-4) and their aunt (II-3) were heterozygous for RAB32 Ser71Arg, and presented with resting tremor at ages 60, 40, and 81 years, respectively (table 3). The gene discussed is RAB32; the disease is Parkinson disease.