The change in IGF-I in μg/L/week, gestational age in weeks and a week of predominant donor human milk feeding were associated with the occurrence of BPD in the multivariable analysis (respectively, OR 0.63 (0.43–0.92), OR 0.44 (0.26–0.76) and 7.6 (1.2–50.4)). This evidence concerns the gene IGF1 and bronchopulmonary dysplasia.