MMP9 and hypertensive disorder: Contrary to the results obtained, although the sample in the present study is clinically healthy, Valente et al. evaluated the expression of MMP-9 in groups with hypertensive crises, controlled hypertension, and normotensives, and statistically significant results were obtained that proved that the group in with emerging hypertensive crises presented higher levels of MMP-9 compared to the normotensive group, supporting that MMP-9 levels are related to inflammatory processes and an increased risk of CD [77].