Similarly to DYNLT3, P4HA3 silencing significantly decreased mesenchymal markers (VIM, N-cadherin and Snail) expression and increased E-cadherin as an epithelial marker, while its overexpression produced the opposite effects, promoting cancer growth and metastasis by affecting the transforming growth factor-beta 1 (TGF-β) signaling pathway [152], which has a significant role in BC initiation and promotion and is linked to health disparities in AA [153,154]. Here, DYNLT3 is linked to breast cancer.