POLQ and breast cancer: Family et al. (2014) analyzed single-nucleotide polymorphisms (SNPs) in DNA bypass polymerase genes, such as DNA polymerase theta (POLQ), and their association with BC and BC subtypes in AAW and White women, concluding that the analyzed SNPs are in high linkage disequilibrium in both races, but these can be associated with the risk of luminal BC [54].