Even though most focus has been on identifying drug-like molecules with potential as cognitive enhancers [12,30,31], e.g., for future treatment of Alzheimer’s disease, the important roles of IRAP in antigen cross-presentation [32] and T-cell receptor signaling [33], as well as neuroprotection in ischemic stroke model [34], has also attracted attention in drug discovery contexts. The gene discussed is LNPEP; the disease is ischemic stroke.