ABCC8 and hyperinsulinism: Regarding glucose metabolism, more than 100 mutations in SUR1/Kir6.2 channels have been identified that are associated with channelopathies, for example, the recessive form of persistent hyperinsulinemic hypoglycemia of the child, or infantile hyperinsulinemia, and at least two other persistent types of prenatal hypoglycemia [21,22].