Based on the obscured correlations and even negative correlation between the extent of HPτ, Aβ, αS, TDP43, and age (Table 6) in individuals with dementia, it would not be surprising if anti-Aβ treatment would, over time, lead to an increased number of individuals with dementia with PART in Braak stages V–VI, or even to a new type of dementia disorder. Here, TARDBP is linked to dementia.