Two significant pathways, hsa04080, Neuroactive ligand-receptor interaction, and hsa04950, Maturity onset diabetes of the young (MODoY; with transcription factors FOXA3, NKX6-1, MAFA, PAX6, PDX1), were identified for the genes expressed more highly in the high-CCNE1 tumours. This evidence concerns the gene CCNE1 and neoplasm.