MPO and acute respiratory distress syndrome: Thus, high levels of NET formation have been described for the bacterial origin (pneumonia) of ARDS or ventilation pneumonia [40], while there is a correlation between the severity of ARDS and NET serum level [41], as well as between the NET (evaluated by MPO-DNS complex) level and the severity of organ dysfunction and 28-day mortality in sepsis and septic shock [39,40].