S100A4 and neoplasm: The induction of some proteins that were overexpressed in our CT26-bearing spleen model has been previously reported and it led to a poor prognosis in colorectal patients, such as Carbonic anhydrase IX (fold change tumor/control: FC: 26.155) [62,63], protein S100A4 (FC: 23.44) [64], and galectin-1 (FC: 10.25) [65,66].