HMGB1 and colorectal cancer: Additionally, the following proteins were previously reported to contribute to colorectal cancer progression and poor prognosis and were induced in the secondary CT26 tumor-bearing livers: galectin-3 (FC: 73.4) [67], proliferation marker protein Ki-67 (FC: 37.3) [68], and the High Mobility Group Protein 1 (FC: 25.7) [69].