Later, Yigit et al. (2016) reported that upon transplantation of an aggressive murine B220+ CD5+ CLL cell clone, TCL1-192, into SCID mice, one injection of an anti-SLAMF6/CD352 monoclonal antibody abrogated tumor progression in the spleen, bone marrow, and blood, but not in the peritoneal cavity or omentum [34]. The gene discussed is SLAMF6; the disease is B-cell chronic lymphocytic leukemia.