The results identified a significant negative association between GPC4 gene expression levels and survival in cancer patients with uveal melanoma (TCGA-UVM), pancreatic carcinomas (TCGA-PAAD), lower grade glioma (TCGA-LGG) and brain glioblastoma (TCGA-GBM) (Figure 2A, bold; list of TCGA cancer abbreviations has been provided in Supplementary Table S1). This evidence concerns the gene GPC4 and central nervous system cancer.