CXCL8 and colorectal carcinoma: Although the role of CXCL8 is reported to be controversial in cancer, Li et al. [71] found that CXCL8 may be functional as an antitumor immune response in the TME of patients affected by colorectal cancer (CRC) through the stimulation of dendritic cells (DCs), essential for T-cell activation [71].