CD274 and neoplasm: In the case of chRCC, PD-L1 positivity in TIMCs did not correlate with any of the examined clinicopathological features such as age during surgery, sex, pathological tumor stage, WHO/ISUP grade, presence of tumor necrosis, angioinvasion, neuroinvasion, renal fibrous capsule invasion, perinephric fat invasion and risk of death (Table 3).