Autocrine signaling of fibroblast growth factors (FGF) and their receptors (FGFR) has been shown in NSCLC cell lines [71,72], and activation of an FGF2–FGFR1 autocrine loop has been reported in EGFR-TKI-resistant cell lines [73]. Here, EGFR is linked to non-small cell lung carcinoma.