The network of the small plum4 module (Figure 7) is characterized by the presence of many lncRNAs, including SATB2-AS1, special AT-rich sequence binding protein 2 antisense RNA 1 (MM = −0.9; kWithin scaled = 0.6; GSERL-resistance and GSEMT intermediate phentotype = 0.8), which has been reported to promote tumor cell growth in osteosarcoma [86], and NSCLC [87]; in contrast, it inhibits tumor cell metastasis in colorectal cancer through positive regulation of SATB2 gene expression [88]. The gene discussed is SATB2; the disease is osteosarcoma.