Moreover, ILC2 and Th2 cells, alongside mast cells, basophils, and eosinophils, are significant sources of other inflammatory agents, including IL-4, IL-13, IL-5, prostaglandin D2, and cysteinyl leukotrienes, which further contribute to the inflammatory milieu in CRSwNP. The gene discussed is IL5; the disease is chronic rhinosinusitis with nasal polyps.