EPHB1 and EPHB3 are overexpressed in rhabdomyosarcoma tumor cells [121], while EPHB2 high-level expression has been reported in medulloblastoma tumor tissue samples [66,67], in NF2-deficient meningioma cell lines [98], and rhabdomyosarcoma tumor cells [121]. This evidence concerns the gene EPHB1 and medulloblastoma.