A total of 125 rare variants were located in 16 different genes with a definite association with DCM: one in ACTC1 (0.8%), three in ACTN2 (2.4%), one in BAG3 (0.8%), one in DES (0.8%), four in DSP (3.2%), two in FLNC (1.6%), two in JPH2 (1.6%), four in LMNA (3.2%), five in MYH7 (4%), six in RBM20 (4.8%), two in SCN5A (1.6%), two in TNNC1 (1.6%), one in TNNI3 (0.8%), six in TNNT2 (4.8%), eighty-one in TTN (64.8%), and four in VCL (3.2%). This evidence concerns the gene RBM20 and familial dilated cardiomyopathy.