Assessment of glomerular cellularity in mesangial and endocapillary regions using CD68 immunohistochemistry (IHC) has been studied in proliferative glomerulonephritis, IgA nephropathy (Figure 4), and other immune-complex-mediated glomerulonephritis, such as infection-related glomerulonephritis and SLE nephritis (Table 1 and Table 2). The gene discussed is CD68; the disease is lupus nephritis.