PLA2G4A (phospholipase A2 group IVA), RNLS (renalase, an FAD-dependent amine oxidase), and HLA-DOA (major histocompatibility complex class II DO alpha) were downregulated by NTD treatment, although they were not upregulated in patients with IPF compared with HCs. This evidence concerns the gene PLA2G4A and idiopathic pulmonary fibrosis.