We base this rationale on the observation that silencing Dhx15 in mice with the AUMsilence ASO Dhx15 treatment does have a clear impact on reducing the size of the primary tumor, since these specific anti-Dhx15 oligo sequences further reduce the presence of Dhx15 compared to the levels of Dhx15 expression found in the Dhx15+/− mice. Here, DHX15 is linked to neoplasm.