Intriguingly, in comparison to the previous analysis, we observed 6 new non-synonymous SNVs linked to hematological disease, including variations in CBL (1 pt); DNMT3A (3 pts); FLT3 (1 pts), NQO1 (1 pt); NRAS (1 pts) and 2 frameshifts: CEBPA (1 pts) and NBN (1 pts). Here, NBN is linked to hematologic disorder.