Detailed in vitro and in vivo studies confirmed that CUR reduces the release of inflammatory cytokines from monocytes and macrophages (interleukin-8, IL-8 and tumor TNF-α) and also inhibits the enzymes involved in inflammation—cyclooxygenase 2 (COX-2) and lipoxygenase (LOX) [17]. This evidence concerns the gene PTGS2 and neoplasm.