ADAMTS8 and neoplasm: Moreover, a panel consisting of eight genes associated with the extracellular matrix (FERMT1, CTSV, CPS1, ENTPD2, SERPINB5, ITGA8, ADAMTS8, and LYPD3) has been constructed, which has been linked to shorter survival, worse immunological outcomes, and higher tumor purity in lung adenocarcinoma patients [47].