Our findings regarding the significant increase in the concentrations of various autophagy proteins, including Ulk-1, ATG13, Beclin-1, ATG5, ATG12, and ATG9A, in kidneys affected by CIS-induced ATN compared to sham controls indicate an activation of autophagy in response to CIS insult. Here, ATG12 is linked to oculocutaneous albinism type 1.