At line 1 of Table 1, the ratio C4/C3, indicating Short-Chain Acyl-Coenzyme A Dehydrogenase Deficiency is shown as the most modified indicator (12.4-fold increase in treated samples vs. ctrl), while the third most modified (line 3) was the ratio C4/C2, indicating Isobutyryl Coenzyme A Dehydrogenase Deficiency (5.37-fold increase in treated samples vs. ctrl). The gene discussed is C4A; the disease is hyperinsulinemic hypoglycemia, familial, 4.