Co-expression of A1CF and WT NKRF, but not A1CF and NKRF∆(204-308), restored the decrease in IFN-β protein expression and p65 S536 phosphorylation in A1CF-overexpressing stable cells (Figure 6A), which is consistent with A1CF-driven renal cancer cell proliferation detected by the MTT assay (Figure S4A). This evidence concerns the gene IFNB1 and renal carcinoma.