The authors revealed that eucalyptal A downregulated serine/arginine-rich splicing factor 1 (SRSF1) expression and rectified SRSF1-guided abnormal alternative splicing of MYO1B mRNA, which led to anti-GBM activity through the PDK1/AKT/c-Myc and PAK/Cofilin axes. The gene discussed is AKT1; the disease is glioblastoma.