Wei et al. [31] (2022) found that after oral CCM (100 mg/kg/d) for 14 consecutive days in mice with DSS-induced colitis, the levels of CD19CD27 memory B cells in the peripheral blood of colitis mice were significantly reduced, and the expressions of Bcl-6, CIN85, Syk, and p-Syk in colonic tissue were significantly inhibited. This evidence concerns the gene SH3KBP1 and colitis.