The results showed that H-120 may achieve an anti-erythroleukemia effect through the Ras/Raf/MEK/ERK signal pathway and STAT3/c-Myc pathway in vitro, and it has a good effect on the treatment of erythroleukemia mice, suggesting that H-120 may be a potential chemotherapeutic drug for patients with erythroleukemia. This evidence concerns the gene MYC and erythroleukemia.