The anti-apoptotic members of the Bcl-2 family, such as Bcl-2 (B cell leukemia or lymphoma gene number2) and Bcl-xL (B cell lymphoma-extra-large), are frequently overexpressed in neoplasia to inhibit apoptotic cell death during tumorigenesis [27]. Here, BCL2 is linked to B-cell non-Hodgkin lymphoma.