In contrast, the multivariable analysis revealed that decreased maximum signal intensity of the tumor, “en plaque growth”, and the presence of intratumoral calcification were significant predictors of NF-2 copy number loss, with odds ratios of 0.98 (p = 0.015), 0.20 (p = 0.023), and 5.39 (p = 0.021), respectively (Table S4, Figure S4). This evidence concerns the gene NF2 and neoplasm.