A 1-natural-log-unit increase in triglycerides was associated with a 2.54-fold higher risk of diabetes (odds ratio, OR, 2.54; 95% CI, 2.23–2.89; p < 0.001; Model 5, Table 2) after adjustment for risk factors except for the tested mediators (i.e., LDL cholesterol, HOMA for insulin resistance, and C-reactive protein). This evidence concerns the gene CRP and Insulin resistance.